Set in the early 1960s, The Mystery of the Caribbean Pearls follows young Biff Brewster as he visits his Uncle Charlie to discover priceless pearls in Martinique. Even worse, his uncle's friend has gone missing, leaving behind an anxious yet determined son. It is up to Biff Brewster and his new friend Derek to adventure through the Caribbean, dodging nefarious looters and kidnappers to find the hidden treasure and rescue Derek's father.